PHI - Phase Holographic Imaging » Articles & Book Chapters » Characterization of a Transgenic Mouse Model Exhibiting Spontaneous Lung Adenocarcinomas With a Metastatic Phenotype

Characterization of a Transgenic Mouse Model Exhibiting Spontaneous Lung Adenocarcinomas With a Metastatic Phenotype

PLOS ONE, 2017 | Hsuen-Wen Chang, Zih-Miao Lin, Min-Ju Wu, Li-Yu Wang, Yen-Hung Chow, Shih Sheng Jiang, Hui-Ju Ch’ang and Vincent HS Chang

The authors have developed a mouse model which is very similar to human, and which can be used for more relevant drug evaluations. Focus are is tumor metatasis and especially the phenomenon of the epithelial-mesenchymal transition (EMT). HoloMonitor was used to investigate the capability of cell movement of tumor cells at different stages.

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