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The HoloMonitor time-lapse cytometers allow cellular behavior to be continuously quantified and monitored.
Conventional cytometric methods are highly invasive and have poor temporal resolution. This makes them unsuited to study living cells. Artifacts induced by the method and overlooked cellular events may easily lead to incorrect conclusions.
Directly in the cell culture vessel, HoloMonitor records microscopy images at regular time intervals to not overlook any significant events. After recording, the cytometric software will automatically identify and track individual cells over time.
Quantitative phase shift measurements are translated by sophisticated software algorithms into morphological parameters – optical cell volume, thickness, texture and many more – to provide label-free kinetic cell analysis.