Cell morphology is essential in identifying the shape, structure, form, and size of cells and provides key information about cell health. Together with cell proliferation, i.e. cell count and confluence, morphological parameters are also useful in toxicity analyses. HoloMonitor® is designed to monitor changes in cell morphology over time. The analysis includes data for both individual cells and entire populations at the same time, allowing for non-invasive, fast and reliable toxicity studies.
Some of the morphological parameters that can be analyzed using HoloMonitor.
A vast line of morphological parameters can be determined over time using HoloMonitor. Changes in morphological parameters precede dramatic cellular events like mitosis and cell death, and therefore used as early and sensitive markers for detection of various drug effects and mode of actions. As all HoloMonitor applications morphology assessment is cell-friendly and analysed without the use of any labels or stains. Morphological parameters are, for example, useful
Morphology assessment can be used stand alone or in combination with other applications as cell proliferation, cell motility and migration and cell cycle monitoring.
The shape of cells changes continuously as cells move and divide. Using the HoloMonitor, these changes can be monitored and quantified.
Phase Holographic Imaging PHI AB
Scheelevägen 22
223 63 Lund
Sweden
Scheelevägen 22
223 63 Lund
Sweden
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